Baseball Opening Day 2025 Games 2025. On that day, as part of interleague matchups, the yankees will face off the brewers and the mets will face off the. From the tokyo series and opening day through the end of the regular season, here are the key dates to know on the 2025 mlb schedule.

There will also be some notable faces in new places, such as juan soto with the mets (at astros), corbin. The 14 games on opening day will feature four divisional matchups and four interleague contests.